U.S., April 15 -- ClinicalTrials.gov registry received information related to the study (NCT07529002) titled 'Clinical Application of 89Zr-s-C1 PET/CT Imaging in Solid Tumors' on March 20.
Brief Summary: This project is driven by clinical needs and focuses on the mucin (MUC) family, key glycopeptide antigens involved in mediating immune evasion in solid tumors. We selected multiple members of this family as research subjects. Based on the MUC18 target, we developed the probe ⁸⁹Zr-SS-CNB001 (HuAA98-14, hereafter referred to as ⁸⁹Zr-s-C1). Studies have demonstrated that ⁸⁹Zr-s-C1 PET/CT enables noninvasive in vivo identification of tumor lesions in patients with solid tumors, and its imaging efficacy posit...