U.S., March 19 -- ClinicalTrials.gov registry received information related to the study (NCT07479225) titled 'Circulating Cell-Free DNA for Brain Abscess Diagnosis: A Pilot Study' on March 12.
Brief Summary: Brain abscess is a severe intracranial infection associated with significant morbidity and mortality. Standard management combines neurosurgical intervention, when feasible, with prolonged intravenous antibiotic therapy. Neurosurgical procedures, such as surgical drainage or stereotactic aspiration, play a key role in reducing intracranial pressure, decreasing the infectious burden, and obtaining samples for microbiological identification.
However, neurosurgical intervention is not always possible due to technical limitations or patie...