U.S., July 22 -- ClinicalTrials.gov registry received information related to the study (NCT07718152) titled 'Ciprofol and Remimazolam for Intraoperative Neurophysiological Monitoring During Spine Surgery' on July 17.
Brief Summary: Intraoperative neurophysiological monitoring, including motor evoked potentials and somatosensory evoked potentials, is commonly used during spine surgery to help detect impending neurological injury. The quality of these signals can be affected by anesthetic agents. Ciprofol and remimazolam are newer intravenous hypnotic agents that may be suitable for total intravenous anesthesia during procedures requiring neurophysiological monitoring, but direct within-patient comparisons between the two agents are lacking....