U.S., April 30 -- ClinicalTrials.gov registry received information related to the study (NCT07555678) titled 'Chemoradiotherapy and Anti-PD-1 Antibody in Anal Squamous Cell Cancer：Chase' on April 16.
Brief Summary: Squamous cell carcinoma (SCC) of the anus is a rare malignancy. For localized anal squamous cell carcinoma , definitive chemoradiotherapy is the standard treatment. Patients who do not achieve complete response （CR）or experience recurrence require radical surgery with permanent colostomy.
In previous studies of anal squamous cell carcinoma （ASCC）, although favorable response rates were achieved after concurrent chemoradiotherapy, high rates of local recurrence and distant metastasis were also ...