Clinical Trial: Biofilm-induced Antimicrobial Resistance RIsk ERadication in Critical Care Central Venous Catheters

U.S., April 24 -- ClinicalTrials.gov registry received information related to the study (NCT07546994) titled 'Biofilm-induced Antimicrobial Resistance RIsk ERadication in Critical Care Central Venous Catheters' on March 17.

Brief Summary: Central venous catheter (CVC) infections are a frequent and serious nosocomial complication in critical care, leading to increased morbidity, mortality, and costs. The pathophysiology of these infections relies on the formation of a biofilm, an organized microbial structure that confers exceptional tolerance to anti-infectives and the immune system. However, data concerning the characteristics of the in vivo biofilm (kinetics, composition, endo- vs. extraluminal organization) on central venous catheters i...