U.S., May 27 -- ClinicalTrials.gov registry received information related to the study (NCT07607353) titled 'Biodegradable Stents in Primary Sclerosing Cholangitis' on April 20.
Brief Summary: In patients with PSC, endoscopic therapy of strictures aims to improve cholestasis by relieving the biliary obstruction via endoscopic biliary dilatation with consideration of plastic stents in strictures refractory to dilatation due to the risk of pancreatitis and cholangitis . Short term stents have been shown to have similar recurrence-free rates compared to dilatation in a randomised control trial; however, this was terminated after interim analysis due to higher rates of serious adverse events in the stent group. The long term benefits are unclea...