U.S., June 30 -- ClinicalTrials.gov registry received information related to the study (NCT07674537) titled 'Bilirubin Thresholds in Preterm Infants on Neonatal Intensive CarE Units: The B-NICE Trial' on June 11.
Brief Summary: Rationale: Neonatal hyperbilirubinemia is highly prevalent in very preterm infants born 80% of very preterm infants receive phototherapy for several days, accompanied by repeated blood sampling and reduced opportunities for skin-to-skin care. The corresponding UK National Institute for Health and Care Excellence (NICE) guideline applies higher (less strict) thresholds, which may reduce overtreatment, but comparative safety for very preterm infants has not been established in a randomized trial. The investigators hyp...