U.S., April 9 -- ClinicalTrials.gov registry received information related to the study (NCT07517042) titled 'ASCEND-1: Lifestyle Intervention Plus Mazdutide for Weight Management' on March 18.
Brief Summary: Obesity is a chronic, progressive, and relapsing disease. Although lifestyle interventions and anti-obesity medications are effective for inducing weight loss, evidence regarding their role in long-term weight maintenance after pharmacologically induced weight reduction remains limited. In addition, the high cost and potential adverse effects of weight-loss medications restrict their prolonged use, and it is unclear whether low dose medication, intensive life style intervention or together can serve as an effective strategy for weight ...