Clinical Trial: Application and Comparison of [68Ga]Ga-FAPI-04 PET, [18F]FDG PET, and Contrast-Enhanced MRI in Predicting Pathological Response to Neoadjuvant Chemotherapy in Breast Cancer Patients

U.S., April 29 -- ClinicalTrials.gov registry received information related to the study (NCT07553741) titled 'Application and Comparison of [68Ga]Ga-FAPI-04 PET, [18F]FDG PET, and Contrast-Enhanced MRI in Predicting Pathological Response to Neoadjuvant Chemotherapy in Breast Cancer Patients' on April 14.

Brief Summary: This is a prospective, single-center cohort study enrolling patients with axillary lymph node-positive or locally advanced breast cancer, consistent with the indications for neoadjuvant therapy in routine clinical practice and as recommended by local guidelines. Different neoadjuvant chemotherapy (NAC) regimens were selected according to breast cancer subtypes. All patients underwent 68Ga-FAPI PET/MRI, 18F-FDG PET/CT, and co...