U.S., March 26 -- ClinicalTrials.gov registry received information related to the study (NCT07492134) titled 'APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis)' on March 11.
Brief Summary: The goal of this clinical trial is to determine whether antibiotics improve recovery from acute uncomplicated diverticulitis (AUD) in racially and ethnically diverse United States clinical practice. The main questions it seeks to answer are:
* What is the feasibility for completing a subsequent definitive efficacy trial of antibiotics vs. placebo to treat AUD?
* What are the needs for successful recruitment of racial and ethnic subgroups?
* What are the effects of a placebo compared to antibiotics for AUD on a range of key p...