U.S., April 18 -- ClinicalTrials.gov registry received information related to the study (NCT07536152) titled 'Antihistamine for Prevention of HTR After Blood Primed CPB' on April 11.
Brief Summary: This study was a randomized, double-blinded, placebo-controlled study, will be conducted at a university hospital. Forty children undergoing elective repair of congenital heart defect will be included. The patients will randomly allocated (20 patients in each group) to receive a single dose of combined chlorpheniramine or normal saline intravenously immediately after separation from CPB prior to protamine administration.
Study Start Date: March 01
Study Type: INTERVENTIONAL
Condition:
Blood Transfusion Associated Adverse Reactions
Intervent...