Clinical Trial: Antibiotic Tissue Penetration and Tissue Response in Head and Neck Infection and Reconstructive Surgery

U.S., Oct. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07896239) titled 'Antibiotic Tissue Penetration and Tissue Response in Head and Neck Infection and Reconstructive Surgery' on Oct. 20.

Brief Summary: The goal of this study is to measure how well commonly used antibiotics reach the tissue in the head and neck region in adults with a postoperative neck infection or undergoing reconstructive nasal surgery with an inferior turbinate flap. The study also describes markers of ischemia and inflammation in the newly created flap during the first days after surgery.

The main question it aims to answer is: For how long do the free concentrations of cefuroxime, cloxacillin, dicloxacillin, and amoxicillin/clav...