Clinical Trial: Anti-TNFα Therapy for Improving Pregnancy Rates in Endometriosis Patients With Failed ICSI

U.S., April 4 -- ClinicalTrials.gov registry received information related to the study (NCT07509411) titled 'Anti-TNFα Therapy for Improving Pregnancy Rates in Endometriosis Patients With Failed ICSI' on March 29.

Brief Summary: This prospective study targets infertile women with endometriosis (EM) who have experienced a previously failed Intracytoplasmic Sperm Injection (ICSI) trial. Using the P-I-C-O framework, the study evaluates whether the administration of an anti-TNF-α therapy (Intervention) 4-5 days before a frozen blastocyst transfer (FBT) improves reproductive outcomes compared to standard protocols (Comparison). The primary outcome is the clinical pregnancy rate, with secondary outcomes focusing on implantation, ongoin...