U.S., April 23 -- ClinicalTrials.gov registry received information related to the study (NCT07544784) titled 'AK104 Plus Radiotherapy Combined With Standard Therapy Versus Standard Therapy as First-Line Treatment for pMMR/MSS CRLM (APSOC)' on April 01.

Brief Summary: This is a prospective, randomized controlled, single-center phase II clinical study. It aims to compare the efficacy of AK104 plus radiotherapy combined with standard therapy versus standard therapy as first-line treatment for liver metastases from metastatic colorectal cancer.

Study Start Date: Nov. 04, 2025

Study Type: INTERVENTIONAL

Condition: Colorectal Cancer Liver Metastases (CRLM)

Intervention: DRUG: AK104 with radiotherapy

AK104 with radiotherapy combined with s...