U.S., March 6 -- ClinicalTrials.gov registry received information related to the study (NCT07451886) titled 'Adjunctive Fludrocortisone in Septic Shock' on Jan. 28.
Brief Summary: Sepsis is a life-threatening condition caused by the body's dysregulated response to an infection. While corticosteroids are known to help stabilize blood pressure in septic shock, their ability to reduce mortality is still debated. Recent analyses suggest that combining fludrocortisone with hydrocortisone may be more effective at saving lives than hydrocortisone alone.
To test this hypothesis, a large, definitive international trial is needed. However, this research proposal is for a smaller pilot study (Phase II) involving 32 critically ill patients. The prima...