Clinical Trial: Adjunctive Antioxidant Effect of Centella Asiatica Nanoemulsion Gel in Management of Periodontitis

U.S., July 14 -- ClinicalTrials.gov registry received information related to the study (NCT07697209) titled 'Adjunctive Antioxidant Effect of Centella Asiatica Nanoemulsion Gel in Management of Periodontitis' on Jan. 18.

Brief Summary: The aims of the current study are:

1. Evaluation of the clinical efficacy of local delivery of nanoemulsion gel containing Centella asiatica extract as an adjunct to conventional non-surgical periodontal therapy in periodontitis patients.

2. Evaluation of the antioxidant effect of this treatment by the assessment of nuclear factor erythroid 2-related factor 2 (NrF2) and glutathione peroxidase 1 (GPX1) in the gingival crevicular fluid (GCF) samples.

Study Start Date: March 21, 2025

Study Type: INTERVENTIO...