Clinical Trial: A Trial of Intraoperative Fibrin Sealant on Postoperative Recovery After Total Knee Replacement

U.S., March 7 -- ClinicalTrials.gov registry received information related to the study (NCT07455591) titled 'A Trial of Intraoperative Fibrin Sealant on Postoperative Recovery After Total Knee Replacement' on Feb. 25.

Brief Summary: This study is conducted as a pilot trial to assess the added benefit of the VeraSeal fibrin sealant to TXA on postoperative outcomes following TKR. Informed consent is obtained from all participants prior to inclusion in the study. Patients are prospectively recruited from a consecutive series of TKR procedures performed for end-stage osteoarthritis. Recruited patients were randomised into two cohorts: those receiving intra-articular tranexamic acid (TXA) alone, and those receiving intra-articular TXA and VeraS...