U.S., Feb. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07424625) titled 'A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac Surgical Patients' on Feb. 14.
Brief Summary: The purpose of this research is to determine if two commonly used medications to treat metabolic acidosis in the setting of cardiac surgery, sodium bicarbonate and THAM, are equivalent.
Study Start Date: Feb., 2026
Study Type: INTERVENTIONAL
Condition:
Metabolic Acidosis
Intervention:
DRUG: Sodium bicarbonate
Patients in the ICU following cardiothoracic surgery with use of cardiopulmonary bypass and requiring treatment for metabolic acidosis (base excess less than -5), will receive sodium bicarb...