Clinical Trial: a Salivary Cell-free RNA Liquid Biopsy Model for Non-invasive Diagnosis in Sjogren's Disease

U.S., Sept. 18 -- ClinicalTrials.gov registry received information related to the study (NCT07824440) titled 'a Salivary Cell-free RNA Liquid Biopsy Model for Non-invasive Diagnosis in Sjogren's Disease' on Sept. 07.

Brief Summary: The goal of this observational study is to learn whether salivary cell-free RNA (cfRNA) can be used as a non-invasive liquid biopsy test to help diagnose Sjogren's disease (SjD) and understand disease-related changes in the salivary glands. The main questions it aims to answer are:

* Can salivary cfRNA distinguish patients with SjD from people with sicca symptoms who do not have SjD?

* Are salivary cfRNA signals associated with clinical features of SjD, such as autoantibody-related immune activity and salivary...