U.S., March 5 -- ClinicalTrials.gov registry received information related to the study (NCT07448298) titled 'A Clinical Study of AFN50 in the Treatment of Autoimmune Diseases' on Feb. 26.
Brief Summary: This study is a single-arm, open-label, single-centre exploratory clinical trial designed to evaluate the safety, tolerability, and preliminary efficacy of AFN50 Injection in adult patients with B-cell-mediated refractory/replapased autoimmune diseases.
Study Start Date: March 01
Study Type: INTERVENTIONAL
Condition:
Relapsed/Refractory Autoimmune Diseases
Intervention:
BIOLOGICAL: AFN50 injection
Intravenous infusion therapy. AFN50 was developed using novel T-cell-targeted lipid nanoparticles (T-LNP) that encapsulate RNA encoding a ...