U.S., June 2 -- ClinicalTrials.gov registry received information related to the study (NCT07616999) titled 'A 20-Year Follow-up of First Episode Psychosis: Longitudinal Effects of Early Treatment Strategies and Relapse' on May 13.
Brief Summary: The study aims to address the following questions:
1. Do subgroups defined by early medication choices, relapse, and medication taken over 20 years differ in clinical, cognitive, and functional outcomes?
2. What are the long-term cognitive functioning trajectories, what factors predict these trajectories, and how do they relate to outcomes?
3. What might be the mechanisms behind medication discontinuation and poor long-term outcome, including the roles of multiple relapses and treatment resistan...