U.S., Aug. 29 -- ClinicalTrials.gov registry received information related to the study (NCT07792369) titled '26DT052; Scaling Busulfan Dose to Body Surface Area in Children' on Aug. 25.
Brief Summary: The goal of this pilot study is to determine if scaling the first busulfan dose to Body Surface Area (BSA) in children with a BSA >=0.5 m2 and using a BSA-banded dosing table for infants (BSA <0.5 m2) increases the fraction of patients achieving a therapeutic drug exposure after the first dose.
Study Start Date: Sept., 2026
Study Type: INTERVENTIONAL
Condition:
Busulfan Pharmacokinetic Analysis
Busulfan Dosing
Hematopoietic Stem Cell Transplant (HSCT)
Busulfan
Glutathione
Intervention:
DRUG: Busulfan (BU)
Busulfan is a cell cycle non-s...