Pakistan, Sept. 10 -- Sandra Bullock has opened up about one of the most difficult periods of her life, reflecting on divorce, motherhood and her work during personal turmoil. The 62-year-old actress discussed the experience during a conversation with longtime friend Jennifer Aniston for Interview magazine. Bullock described filming the 2013 space thriller Gravity as particularly meaningful because it mirrored what she was experiencing at the time.

Bullock was married to Jesse James from 2005 until their divorce in 2010. Their split followed allegations from multiple women that James had been unfaithful, which he later acknowledged. That same year, Bullock adopted her son Louis, now 16, and said the combination of personal upheaval and n...