India, Nov. 14 -- In a breakthrough that changes our understanding of how diabetes develops, researchers at the Indian Institute of Technology Kanpur (IIT Kanpur) have found that immune cells inside the pancreas can switch off insulin release within minutes and have identified the molecular switch that allows them to do it.

The study published in the Journal of Clinical Investigation, one of the leading biomedical journals in the world, was jointly led by Simran Singh and Ashish Kumar, who are the co-first authors of the research, under the supervision of Dr Sai Prasad Pydi at the Department of Biological Sciences and Bioengineering, IIT Kanpur.

The team has also confirmed that the same pathway is present and active in human pancreatic ...