Singapore, Oct. 15 -- Swiss firm Alentis Therapeutics and South Korea based PinotBio have entered into a research collaboration and licensing agreement to discover and develop next-generation antibody-drug conjugates (ADCs) to expand the potential of claudin-1 as a therapeutic target in oncology.

Claudin-1 is overexpressed in more than ten different tumor types, representing a significant opportunity for targeted cancer therapies. Alentis is the leader in developing claudin-1 targeted therapies, with two first-in-class ADC candidates in the clinic, while PinotBio has established itself as a leader in ADC innovation through its PINOT-ADC(R) platform offering a toolbox of novel linkers and payloads. The collaboration aims to combine PinotB...