Singapore, March 2 -- Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) and Monash University in Australia, have demonstrated that an intranasal vaccine booster may confer significantly stronger and broader immune responses, and provide robust neutralising antibody and resident T cell responses in the lung and nasal tissues, outperforming conventional mRNA booster vaccination.

Published in The Journal of Clinical Investigation, the study offers a promising and more effective method for delivering vaccine boosters that may offer stronger protection against infections and maintain optimal immunity.

The study examined alternative vaccine booster candidates and administration methods that ma...