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US Patent Issued to Genentech, Hoffmann-La Roche on Aug. 4 for "Solid forms of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-Bindol-2-yl)-2,2-difluoropropan-1-ol and processes for preparing fused tricyclic compounds comprising a substituted phenyl or pyridinyl moiety, including methods of their use" (American, Swiss Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,284, issued on Aug. 4, was assigned to Genentech Inc. (South San Francisco, Calif.) and Hoffmann-La Roche Inc. (Little Falls, N.J.). "Solid ... Read More


US Patent Issued to Northwestern University on Aug. 4 for "Ring-in-ring complexes exhibiting tunable multicolor photoluminescence" (Illinois Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,285, issued on Aug. 4, was assigned to Northwestern University (Evanston, Ill.). "Ring-in-ring complexes exhibiting tunable multicolor photo... Read More


US Patent Issued to ONO PHARMACEUTICAL on Aug. 4 for "Compound having KDM5 inhibitory activity and pharmaceutical use thereof" (American, British, Japanese Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,286, issued on Aug. 4, was assigned to ONO PHARMACEUTICAL Co. LTD. (Osaka, Japan). "Compound having KDM5 inhibitory activity and pharmaceuti... Read More


US Patent Issued to KEAISE MEDICINE WUHAN on Aug. 4 for "Aryl-fused isoselenazole compound containing tetrazine substituent, synthesis method therefor, and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,287, issued on Aug. 4, was assigned to KEAISE MEDICINE WUHAN CORP. (Wuhan, China). "Aryl-fused isoselenazole compound containing tetrazine s... Read More


US Patent Issued to QURIENT on Aug. 4 for "Compounds having cyclin-dependent kinase(CDK)-inhibitory function" (South Korean Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,288, issued on Aug. 4, was assigned to QURIENT Co. LTD (Gyeonggi-Do, South Korea). "Compounds having cyclin-dependent kinase(CDK)-inhibitory... Read More


US Patent Issued to HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY on Aug. 4 for "Solid forms of pharmaceutically acceptable salts of (S)-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl)-4,6-dihydropyrrolo[3,4-dimidazol-5(1H)-yl)(3-hydroxypyrrolidin-1-yl)methanone as JAK inhibitors" (Chinese Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,289, issued on Aug. 4, was assigned to HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY Co. LTD. (China). "Solid forms of pharmaceutically acceptable... Read More


US Patent Issued to Blueprint Medicines on Aug. 4 for "Synthetic methods and intermediates for producing compounds for treating KIT- and PDGFRA-mediated diseases" (French, American, Swiss Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,290, issued on Aug. 4, was assigned to Blueprint Medicines Corp. (Cambridge, Mass.). "Synthetic methods and intermediates for producing comp... Read More


US Patent Issued to ACURASTEM on Aug. 4 for "PIKfyve kinase inhibitors" (Arizona Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,291, issued on Aug. 4, was assigned to ACURASTEM Inc. (Pasadena, Calif.). "PIKfyve kinase inhibitors" was invented by Martin Smrcina (Oro Va... Read More


US Patent Issued to MINGHUI PHARMACEUTICAL (HANGZHOU), MINGHUI PHARMACEUTICAL (SHANGHAI) on Aug. 4 for "Toxin molecule suitable for antibody-drug conjugate" (Chinese Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,292, issued on Aug. 4, was assigned to MINGHUI PHARMACEUTICAL (HANGZHOU) Ltd. (Hangzhou, China) and MINGHUI PHARMACEUTICAL (SHANGHAI) Ltd. (S... Read More


US Patent Issued to HITGEN on Aug. 4 for "Crystal form of macrocyclic compound, and preparation method therefor and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,293, issued on Aug. 4, was assigned to HITGEN INC. (Chengdu, China). "Crystal form of macrocyclic compound, and preparation method therefor ... Read More