ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,291, issued on Aug. 4, was assigned to ACURASTEM Inc. (Pasadena, Calif.).

"PIKfyve kinase inhibitors" was invented by Martin Smrcina (Oro Valley, Ariz.), Ronghua Li (Oro Valley, Ariz.), Anil Nair (Oro Valley, Ariz.), Paul August (Oro Valley, Ariz.) and Kirsten Bjergarde (Oro Valley, Ariz.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds of formula (I) (shown below) useful as inhibitors of phosphatidylinositol-3-phosphate 5-kinase (PIKfyve) as well as their use for treating diseases and disorders associated with PIKfyve."

The patent was filed on March 21, 2024, under Application No. 18/612,147.

*For further i...