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Clinical Trial: Safety, Adverse Events, and Pharmacokinetics/Therapeutic Drug Monitoring of Sirolimus in Infants Under One Year of Age: A Scoping Review (Japan)

Tokyo, Sept. 28 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063067) titled 'Safety, Adverse Events, and Pharmacokinetics/Therapeutic Drug Monitoring o... Read More


Clinical Trial: Needs for sleep support and nursing practices for infants aged 1-2 months and their caregivers: A multicenter cross-sectional survey of mothers, partners, and nursing professionals (Japan)

Tokyo, Sept. 28 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063065) titled 'A survey of sleep support needs among infants aged 1-2 months and their fa... Read More


Clinical Trial: Effects of Continuous Test Food Intake on Bowel Movements: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study (Japan)

Tokyo, Sept. 28 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063041) titled 'Effects of Continuous Test Food Intake on Bowel Movements: A Randomized, P... Read More


Clinical Trial: A Morphological Study of the Spine in Pregnant Women in the Third Trimester Using CT Images: A Retrospective Study Comparing Images from the Same Patients During Pregnancy and Non-pregnancy (Japan)

Tokyo, Sept. 28 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000063032) titled 'A Morphological Study of the Spine in Pregnant Women in the Third Trimeste... Read More


Singapore Clinical Trial: A Phase 3, Randomized, Open-Label Study of Rinzimetostat (ORIC-944) in Combination with Darolutamide Compared with ARPI or Docetaxel in Patients with Metastatic Castration Resistant Prostate Cancer Previously Treated with Abiraterone Acetate (Himalayas-1)

Singapore, Sept. 27 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Open-Label Study of Rinzimetostat (ORIC-944) in Combination with Darolutam... Read More


Singapore Clinical Trial: An Interventional Phase 3, Open Label, Randomized Study To Evaluate Efficacy And Safety of PF-08634404 in Combination With Chemotherapy Versus Pembrolizumab in Combination With Chemotherapy in Adult Participants With Advanced or Recurrent Mismatch Repair (MMR) Proficient Endometrial Cancer

Singapore, Sept. 27 -- The Health Sciences Authority received information related to the study titled 'An Interventional Phase 3, Open Label, Randomized Study To Evaluate Efficacy And Safety of PF-086... Read More


Singapore Clinical Trial: A Randomized, Double-blind, Phase 3 Study of Pembrolizumab + Pemetrexed + Platinum Chemotherapy With or Without Zoldonrasib (RMC-9805) as First Line Treatment in Patients With Metastatic Non-squamous RAS G12D-Mutated Non-small Cell Lung Cancer (RASolve 308)

Singapore, Sept. 27 -- The Health Sciences Authority received information related to the study titled 'A Randomized, Double-blind, Phase 3 Study of Pembrolizumab + Pemetrexed + Platinum Chemotherapy W... Read More


Singapore Clinical Trial: A Phase 3, Randomized, Open-Label Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Patients With Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma (RASolute 309)

Singapore, Sept. 27 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Open-Label Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Ve... Read More


Singapore Clinical Trial: A Phase 3, two-part, double-blind, randomized, placebo-controlled study to investigate the safety and efficacy of efimosfermin alfa injection in adult participants with compensated cirrhosis (stage F4 fibrosis) due to metabolic dysfunction-associated steatohepatitis (NEBULA-2)

Singapore, Sept. 27 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, two-part, double-blind, randomized, placebo-controlled study to investigate the safety... Read More


Singapore Clinical Trial: A Phase 3, double-blind, randomized, placebo controlled, 2-arm study to investigate the safety and efficacy of efimosfermin alfa injection in adult participants with compensated cirrhosis due to metabolic dysfunction-associated steatohepatitis (NEBULA-1)

Singapore, Sept. 27 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, double-blind, randomized, placebo controlled, 2-arm study to investigate the safety an... Read More