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Singapore Clinical Trial: CO45042: A Phase III, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Divarasib Plus Pembrolizumab Versus Pembrolizumab And Pemetrexed And Carboplatin or Cisplatin in Patients with Previously Untreated, KRAS G12C-Mutated, Advanced Or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Singapore, May 27 -- The Health Sciences Authority received information related to the study titled 'CO45042: A Phase III, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Divarasib ... Read More


Clinical Trial: Results of Nerve Surgery to Treat PostAmputation Pain

U.S., May 27 -- ClinicalTrials.gov registry received information related to the study (NCT07605754) titled 'Results of Nerve Surgery to Treat PostAmputation Pain' on Sept. 15, 2025. Brief Summary: Ra... Read More


Singapore Clinical Trial: A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Compared with Investigator’s Choice of Chemotherapy (Paclitaxel, Nab-paclitaxel or Gemcitabine + Carboplatin) in Combination With Pembrolizumab in Patients with PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

Singapore, May 27 -- The Health Sciences Authority received information related to the study titled 'A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durv... Read More


Singapore Clinical Trial: TulmiSTAR-01: A two-part, Phase I dose escalation and expansion followed by a randomized, open-label multicenter, Phase II study to assess the safety and efficacy of the combination of tulmimetostat (DZR123) and JSB462 (luxdegalutamide) vs standard of care in patients with progressive metastatic castrate resistant prostate cancer

Singapore, May 27 -- The Health Sciences Authority received information related to the study titled 'TulmiSTAR-01: A two-part, Phase I dose escalation and expansion followed by a randomized, open-labe... Read More


Singapore Clinical Trial: A Master Protocol of an Open-Label, Multi-Drug, Multi-Centre, Phase II Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumour Activity of Novel Combinations in Participants with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (LIBRA)

Singapore, May 27 -- The Health Sciences Authority received information related to the study titled 'A Master Protocol of an Open-Label, Multi-Drug, Multi-Centre, Phase II Study to Evaluate the Safety... Read More


Clinical Trial: An Open-label Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)

U.S., May 27 -- ClinicalTrials.gov registry received information related to the study (NCT07606274) titled 'An Open-label Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBE... Read More


Clinical Trial: Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellitus and Obesity

U.S., May 27 -- ClinicalTrials.gov registry received information related to the study (NCT07605572) titled 'Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellit... Read More


Clinical Trial: Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events

U.S., May 27 -- ClinicalTrials.gov registry received information related to the study (NCT07607587) titled 'Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Thera... Read More


Clinical Trial: Utility of Whole Genome Sequencing in Fetuses With Abnormal Ultrasound Findings

U.S., May 27 -- ClinicalTrials.gov registry received information related to the study (NCT07606989) titled 'Utility of Whole Genome Sequencing in Fetuses With Abnormal Ultrasound Findings' on April 09... Read More


Clinical Trial: Transcutaneous Superior Laryngeal Nerve Stimulation to Upregulate Swallowing Frequency and Urge to Swallow in Patients Living With ALS

U.S., May 27 -- ClinicalTrials.gov registry received information related to the study (NCT07606235) titled 'Transcutaneous Superior Laryngeal Nerve Stimulation to Upregulate Swallowing Frequency and U... Read More