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Singapore Clinical Trial: A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Firmonertinib Compared with Investigator’s Choice of Osimertinib or Afatinib as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic Non-Small-Cell Lung Cancer with Epidermal Growth Factor Receptor P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations (ALPACCA)

Singapore, July 18 -- The Health Sciences Authority received information related to the study titled 'A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety o... Read More


Singapore Clinical Trial: A Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study to Evaluate the Efficacy and Safety of MK-2214 in Participants with Early Alzheimer's Disease

Singapore, July 18 -- The Health Sciences Authority received information related to the study titled 'A Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study to Evaluate the Effic... Read More


Singapore Clinical Trial: Phase 2b, Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Preceded by a Single Ascending Dose Portion and a Phase 2 Open-Label Portion, to Evaluate the Safety and Efficacy of Oral Infigratinib in Infants and Young Children with Achondroplasia

Singapore, July 18 -- The Health Sciences Authority received information related to the study titled 'Phase 2b, Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Preceded by a Single Ascend... Read More


Singapore Clinical Trial: A Phase 3 Open-label Randomized Study Assessing the Efficacy and Safety of RLY-2608 + Fulvestrant Versus Capivasertib + Fulvestrant as Treatment for PIK3CA-mutant Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Locally Advanced or Metastatic Breast Cancer Following Recurrence or Progression On or After Treatment with a CDK4/6 Inhibitor

Singapore, July 18 -- The Health Sciences Authority received information related to the study titled 'A Phase 3 Open-label Randomized Study Assessing the Efficacy and Safety of RLY-2608 + Fulvestrant ... Read More


Clinical Trial: Safety and Efficacy Study of Safusidenib in Participants With Grade 2 IDH1-Mutant Glioma

U.S., July 18 -- ClinicalTrials.gov registry received information related to the study (NCT07712757) titled 'Safety and Efficacy Study of Safusidenib in Participants With Grade 2 IDH1-Mutant Glioma' o... Read More


Clinical Trial: Effect of Intracanal Cryotherapy on Postoperative Endodontic Pain

U.S., July 18 -- ClinicalTrials.gov registry received information related to the study (NCT07710833) titled 'Effect of Intracanal Cryotherapy on Postoperative Endodontic Pain' on July 13. Brief Summa... Read More


Clinical Trial: A Study to Evaluate the Absorption, Distribution, Metabolism, and Excretion of [14C]-MRM-3379

U.S., July 18 -- ClinicalTrials.gov registry received information related to the study (NCT07712718) titled 'A Study to Evaluate the Absorption, Distribution, Metabolism, and Excretion of [14C]-MRM-33... Read More


Clinical Trial: Pericapsular vs Intra-Articular Injection in Adhesive Capsulitis

U.S., July 18 -- ClinicalTrials.gov registry received information related to the study (NCT07710651) titled 'Pericapsular vs Intra-Articular Injection in Adhesive Capsulitis' on July 12. Brief Summar... Read More


Clinical Trial: Comparative Impact of Integrated Neuromuscular Inhibition Technique, Dry Cupping and Dry Needling on Mechanical Neck Pain; A Randomized Controlled Trial

U.S., July 18 -- ClinicalTrials.gov registry received information related to the study (NCT07711041) titled 'Comparative Impact of Integrated Neuromuscular Inhibition Technique, Dry Cupping and Dry Ne... Read More


Clinical Trial: Natural History to Assess Disease in Patients With MPS IIIC

U.S., July 18 -- ClinicalTrials.gov registry received information related to the study (NCT07712003) titled 'Natural History to Assess Disease in Patients With MPS IIIC' on June 15. Brief Summary: Th... Read More