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Singapore Clinical Trial: A Phase 1 Dose Escalation Trial to Determine the Safety, Tolerance, Maximum Tolerated Dose,and Preliminary Antineoplastic Activity of IKS014, a HER2-Targeting Antibody Drug Conjugate(ADC), in Participants with Advanced HER2+ Solid Tumors

Singapore, July 28 -- The Health Sciences Authority received information related to the study titled 'A Phase 1 Dose Escalation Trial to Determine the Safety, Tolerance, Maximum Tolerated Dose,and Pre... Read More


Singapore Clinical Trial: A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab Tirumotecan, MK-2870) Followed by Carboplatin/Paclitaxel vs Chemotherapy, Both in Combination With Pembrolizumab as Neoadjuvant Therapy for High-Risk, Early-Stage, Triple-Negative Breast Cancer or Hormone Receptor-low Positive/Human Epidermal Growth Factor Receptor-2 Negative Breast Cancer

Singapore, July 28 -- The Health Sciences Authority received information related to the study titled 'A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab... Read More


Singapore Clinical Trial: A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig Plus Abiraterone Versus Investigator’s Choice in Participants with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

Singapore, July 28 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig Plus Abiraterone Versus Invest... Read More


Singapore Clinical Trial: Regime for vitamin D maintEnanCe In poSt-operatIVE patients (D-ECISIVE) Randomized Controlled Trial

Singapore, July 28 -- The Health Sciences Authority received information related to the study titled 'Regime for vitamin D maintEnanCe In poSt-operatIVE patients (D-ECISIVE) Randomized Controlled Tria... Read More


Singapore Clinical Trial: A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Firmonertinib Compared with Investigator’s Choice of Osimertinib or Afatinib as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic Non-Small-Cell Lung Cancer with Epidermal Growth Factor Receptor P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations (ALPACCA)

Singapore, July 28 -- The Health Sciences Authority received information related to the study titled 'A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety o... Read More


Singapore Clinical Trial: The effect of two icodextrin exchanges on fluid status and blood pressure control in children on chronic peritoneal dialysis

Singapore, July 28 -- The Health Sciences Authority received information related to the study titled 'The effect of two icodextrin exchanges on fluid status and blood pressure control in children on c... Read More


Clinical Trial: Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue Cancer

U.S., July 28 -- ClinicalTrials.gov registry received information related to the study (NCT07727434) titled 'Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients Wi... Read More


Clinical Trial: Physiotherapy After Breast Reduction Surgery

U.S., July 28 -- ClinicalTrials.gov registry received information related to the study (NCT07729735) titled 'Physiotherapy After Breast Reduction Surgery' on April 27. Brief Summary: Background and P... Read More


Clinical Trial: Acute Effects of Thoracolumbar Fascia Myofascial Release on Cortical Activity: A Sham-Controlled Trial

U.S., July 28 -- ClinicalTrials.gov registry received information related to the study (NCT07728617) titled 'Acute Effects of Thoracolumbar Fascia Myofascial Release on Cortical Activity: A Sham-Contr... Read More


Clinical Trial: Effects of an ACWR-Guided Load Management Intervention on Time-Loss Injury Incidence in Chinese Elite Youth Footballers: A Cluster Randomised Controlled Trial

U.S., July 28 -- ClinicalTrials.gov registry received information related to the study (NCT07727382) titled 'Effects of an ACWR-Guided Load Management Intervention on Time-Loss Injury Incidence in Chi... Read More