Exclusive

Publication

Byline

Location

Singapore Clinical Trial: A randomized, double-blind, placebo-controlled study to evaluate the effect of dupilumab on airway inflammation through assessments of mucus plugging and other lung imaging parameters in patients with chronic obstructive pulmonary disease

Singapore, June 3 -- The Health Sciences Authority received information related to the study titled 'A randomized, double-blind, placebo-controlled study to evaluate the effect of dupilumab on airway ... Read More


Singapore Clinical Trial: CA088-1007: A Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of Arlocabtagene Autoleucel (BMS-986393), a GPRC5D-directed CAR-T Cell Therapy, Versus Standard Regimens in Adult Participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Singapore, June 3 -- The Health Sciences Authority received information related to the study titled 'CA088-1007: A Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety... Read More


Singapore Clinical Trial: A Multinational, Multicenter, Prospective, Randomized, Controlled, Open-Label, Phase 3 Study of Lutetium-177 (177Lu) Rosopatamab Tetraxetan in Combination with Standard of Care Versus Standard of Care Alone in Patients with Prostate-Specific Membrane Antigen (PSMA) Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC) after Androgen Receptor Pathway Inhibitor (ARPI) Treatment

Singapore, June 3 -- The Health Sciences Authority received information related to the study titled 'A Multinational, Multicenter, Prospective, Randomized, Controlled, Open-Label, Phase 3 Study of Lut... Read More


Singapore Clinical Trial: CO45042: A Phase III, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Divarasib Plus Pembrolizumab Versus Pembrolizumab And Pemetrexed And Carboplatin or Cisplatin in Patients with Previously Untreated, KRAS G12C-Mutated, Advanced Or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Singapore, June 3 -- The Health Sciences Authority received information related to the study titled 'CO45042: A Phase III, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Divarasib ... Read More


Singapore Clinical Trial: A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Compared with Investigator’s Choice of Chemotherapy (Paclitaxel, Nab-paclitaxel or Gemcitabine + Carboplatin) in Combination With Pembrolizumab in Patients with PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

Singapore, June 3 -- The Health Sciences Authority received information related to the study titled 'A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durv... Read More


Clinical Trial: MTM2MTG Pilot Ancillary Study

U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07620808) titled 'MTM2MTG Pilot Ancillary Study' on May 27. Brief Summary: We will conduct an ancillary study... Read More


Clinical Trial: Effects of Post Isometric Relaxation in Patients With Quadratus Lumborum Syndrome

U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07619742) titled 'Effects of Post Isometric Relaxation in Patients With Quadratus Lumborum Syndrome' on July 0... Read More


Clinical Trial: Open-Label Extension Study of MHB018A in Patients With Thyroid Eye Disease

U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07620405) titled 'Open-Label Extension Study of MHB018A in Patients With Thyroid Eye Disease' on May 27. Brie... Read More


Clinical Trial: Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study

U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07621445) titled 'Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patien... Read More


Clinical Trial: Parasternal Block Versus Wound Infiltration for Pain After Median Sternotomy:A Salivary Opiorphin-Based Study

U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07621744) titled 'Parasternal Block Versus Wound Infiltration for Pain After Median Sternotomy:A Salivary Opio... Read More