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Singapore Clinical Trial: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Revumenib in Combination with Intensive Chemotherapy in Participants with Newly Diagnosed AML with an NPM1 mutation (REVEAL-ND NPM1)

Singapore, March 27 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Revumenib in Combination with In... Read More


Singapore Clinical Trial: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of GB-0895 Adjunctive Therapy in Adults and Adolescents with Severe Uncontrolled Asthma

Singapore, March 27 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety o... Read More


Singapore Clinical Trial: A Phase 1 randomized, placebo-controlled multiple dose study to characterize the effects of LY4088182 on renal hemodynamics in participants with overweight or obesity.

Singapore, March 27 -- The Health Sciences Authority received information related to the study titled 'A Phase 1 randomized, placebo-controlled multiple dose study to characterize the effects of LY408... Read More


Singapore Clinical Trial: Platelet-Rich Plasma with Hyaluronic Acid Injections for Post- Viral Olfactory loss. A double-blinded RCT

Singapore, March 27 -- The Health Sciences Authority received information related to the study titled 'Platelet-Rich Plasma with Hyaluronic Acid Injections for Post- Viral Olfactory loss. A double-bli... Read More


Singapore Clinical Trial: ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination with Chemotherapy Versus Bevacizumab in Combination with Chemotherapy in Participants with Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Singapore, March 27 -- The Health Sciences Authority received information related to the study titled 'ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination with Chemother... Read More


Singapore Clinical Trial: Leveraging AS01-induced immune cell reprogramming to modulate immune dysregulation in rheumatoid arthritis

Singapore, March 27 -- The Health Sciences Authority received information related to the study titled 'Leveraging AS01-induced immune cell reprogramming to modulate immune dysregulation in rheumatoid ... Read More


Singapore Clinical Trial: A Phase I/II open label study of DJI136, a DLL3-targeted CAR-T therapy, in adult patients with ES-SCLC

Singapore, March 27 -- The Health Sciences Authority received information related to the study titled 'A Phase I/II open label study of DJI136, a DLL3-targeted CAR-T therapy, in adult patients with ES... Read More


Singapore Clinical Trial: Beamion PANTUMOR 1: A Phase II, multicentre, multicohort, open-label trial to evaluate the efficacy and safety of oral zongertinib (BI 1810631) for the treatment of selected HER2 mutated or overexpressed/amplified solid tumours

Singapore, March 27 -- The Health Sciences Authority received information related to the study titled 'Beamion PANTUMOR 1: A Phase II, multicentre, multicohort, open-label trial to evaluate the effica... Read More


Singapore Clinical Trial: An open-label, multi-center, phase I/Ib study of IEV407 as a single agent and in combination with endocrine therapy in patients with advanced hormone receptor positive, HER2- negative breast cancer

Singapore, March 27 -- The Health Sciences Authority received information related to the study titled 'An open-label, multi-center, phase I/Ib study of IEV407 as a single agent and in combination with... Read More


Singapore Clinical Trial: A Phase 3, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Safety and Efficacy of L606 (Treprostinil Liposome Inhalation Suspension) in Participants with Pulmonary Hypertension Associated with Interstitial Lung Disease (WHO Group 3)

Singapore, March 27 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Safe... Read More