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Singapore Clinical Trial: A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Compared with Investigator’s Choice of Chemotherapy (Paclitaxel, Nab-paclitaxel or Gemcitabine + Carboplatin) in Combination With Pembrolizumab in Patients with PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

Singapore, May 12 -- The Health Sciences Authority received information related to the study titled 'A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durv... Read More


Singapore Clinical Trial: TulmiSTAR-01: A two-part, Phase I dose escalation and expansion followed by a randomized, open-label multicenter, Phase II study to assess the safety and efficacy of the combination of tulmimetostat (DZR123) and JSB462 (luxdegalutamide) vs standard of care in patients with progressive metastatic castrate resistant prostate cancer

Singapore, May 12 -- The Health Sciences Authority received information related to the study titled 'TulmiSTAR-01: A two-part, Phase I dose escalation and expansion followed by a randomized, open-labe... Read More


Singapore Clinical Trial: A Master Protocol of an Open-Label, Multi-Drug, Multi-Centre, Phase II Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumour Activity of Novel Combinations in Participants with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (LIBRA)

Singapore, May 12 -- The Health Sciences Authority received information related to the study titled 'A Master Protocol of an Open-Label, Multi-Drug, Multi-Centre, Phase II Study to Evaluate the Safety... Read More


Clinical Trial: A Retrospective Study of the Relationship Between Chest Tube Placement and Pleurodesis Success (Japan)

Tokyo, May 13 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061540) titled 'A Retrospective Study of the Relationship Between Chest Tube Placement and P... Read More


Clinical Trial: A Survey of Satisfaction with Anma Massage and Shiatsu (Finger Pressure Therapy) Provided by Health Keepers for Asthenopia (Japan)

Tokyo, May 13 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061539) titled 'A Survey of Satisfaction with Anma Massage and Shiatsu (Finger Pressure Ther... Read More


Clinical Trial: Effectiveness of a Mobile Application to Promote Mental Health and Parenting Role Development in Women Transitioning to Motherhood: A Randomized Controlled Trial (Japan)

Tokyo, May 13 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061536) titled 'The Effectiveness of Smartphone Apps in Improving Mothers'Mental Health and ... Read More


Clinical Trial: PET/CT and Machine Learning in Severe Brain Injury: A Single-Center Retrospective Study (Japan)

Tokyo, May 13 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061535) titled 'Machine learning using combined positron emission tomography and computed to... Read More


Clinical Trial: Effective Implementation of The Evidence-Based Specific Health Guidance (Japan)

Tokyo, May 13 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061533) titled 'Effective Implementation of The Evidence-Based Specific Health Guidance' on ... Read More


Clinical Trial: A retrospective observational study on the efficacy and safety of FLEND therapy (combination of fludarabine, etoposide, and nelarabine) for relapsed and refractory T-cell acute lymphoblastic leukemia (Japan)

Tokyo, May 13 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061529) titled 'A retrospective survey of FLEND therapy for relapsed or refractory T-cell ac... Read More


Clinical Trial: A non-randomized hybrid type 1 effectiveness-implementation study evaluating the introduction of the Maternal and Child Health Handbook in Adjara, Georgia (Japan)

Tokyo, May 13 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061527) titled 'Study evaluating the introduction of the Maternal and Child Health Handbook ... Read More