Singapore Clinical Trial: A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Firmonertinib Compared with Investigator’s Choice of Osimertinib or Afatinib as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic Non-Small-Cell Lung Cancer with Epidermal Growth Factor Receptor P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations (ALPACCA)

Singapore, July 14 -- The Health Sciences Authority received information related to the study titled 'A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety o... Read More

Singapore Clinical Trial: A Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study to Evaluate the Efficacy and Safety of MK-2214 in Participants with Early Alzheimer's Disease

Singapore, July 14 -- The Health Sciences Authority received information related to the study titled 'A Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study to Evaluate the Effic... Read More

Singapore Clinical Trial: Phase 2b, Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Preceded by a Single Ascending Dose Portion and a Phase 2 Open-Label Portion, to Evaluate the Safety and Efficacy of Oral Infigratinib in Infants and Young Children with Achondroplasia

Singapore, July 14 -- The Health Sciences Authority received information related to the study titled 'Phase 2b, Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Preceded by a Single Ascend... Read More

Singapore Clinical Trial: A Phase 3 Open-label Randomized Study Assessing the Efficacy and Safety of RLY-2608 + Fulvestrant Versus Capivasertib + Fulvestrant as Treatment for PIK3CA-mutant Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Locally Advanced or Metastatic Breast Cancer Following Recurrence or Progression On or After Treatment with a CDK4/6 Inhibitor

Singapore, July 14 -- The Health Sciences Authority received information related to the study titled 'A Phase 3 Open-label Randomized Study Assessing the Efficacy and Safety of RLY-2608 + Fulvestrant ... Read More

Singapore Clinical Trial: A randomized, double-blind, placebo-controlled study to evaluate the effect of dupilumab on airway inflammation through assessments of mucus plugging and other lung imaging parameters in patients with chronic obstructive pulmonary disease

Singapore, July 14 -- The Health Sciences Authority received information related to the study titled 'A randomized, double-blind, placebo-controlled study to evaluate the effect of dupilumab on airway... Read More

Clinical Trial: Appropriateness of Hemostatic Agent Use in Cardiovascular Surgery (HAEMOVAX)

U.S., July 14 -- ClinicalTrials.gov registry received information related to the study (NCT07699016) titled 'Appropriateness of Hemostatic Agent Use in Cardiovascular Surgery (HAEMOVAX)' on June 23. ... Read More

Clinical Trial: Vericiguat and Exercise Hemodynamics in Patients With HFrEF

U.S., July 14 -- ClinicalTrials.gov registry received information related to the study (NCT07697365) titled 'Vericiguat and Exercise Hemodynamics in Patients With HFrEF' on July 05. Brief Summary: He... Read More

Clinical Trial: TSPO Endothelial - EMPATHY

U.S., July 14 -- ClinicalTrials.gov registry received information related to the study (NCT07697183) titled 'TSPO Endothelial - EMPATHY' on May 29. Brief Summary: The aim of the study is to investiga... Read More

Clinical Trial: Effect of Adding Vasopressin on Cardiac Output, Blood Pressure, Diuresis, and Tissue Perfusion Indices in Patients With Septic Shock

U.S., July 14 -- ClinicalTrials.gov registry received information related to the study (NCT07697144) titled 'Effect of Adding Vasopressin on Cardiac Output, Blood Pressure, Diuresis, and Tissue Perfus... Read More

Clinical Trial: Evacuation of Lobar Intracranial Hemorrhage Using Microsurgical Technique (ELIMINATE)

U.S., July 14 -- ClinicalTrials.gov registry received information related to the study (NCT07697742) titled 'Evacuation of Lobar Intracranial Hemorrhage Using Microsurgical Technique (ELIMINATE)' on J... Read More

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