US Patent Issued to ZYMEWORKS BC on Feb. 3 for "Antigen-binding polypeptide constructs comprising kappa and lambda light chains and uses thereof" (Canadian, American Inventors)

ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,540,198, issued on Feb. 3, was assigned to ZYMEWORKS BC INC. (Vancouver, Canada).

"Antigen-binding polypeptide constructs comprising kappa and lambda light chains and uses thereof" was invented by Dunja Urosev (Vancouver, Canada), Stacey A.L. Tom-Yew (Coquitlam, Canada), Leonard G. Presta (San Francisco) and Mario Sanches (Vancouver, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are multispecific antigen-binding polypeptide constructs comprising at least two different heterodimers, each comprising a heavy chain and a light chain. At least one heterodimer comprises a Fab region comprising a lambda light chain and at least one heter...