ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,749, issued on April 14, was assigned to ZP SPV 3 K/S (Soborg, Denmark).

"Compstatin analogues and their medical uses" was invented by Anne Pernille Tofteng Shelton (Soborg, Denmark), Jacob Ulrik Fog (Soborg, Denmark) and Jens Kvist Madsen (Soborg, Denmark).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compstatin analogues having improved binding and complement-inhibiting activity as compared to the 13 amino acid compstatin peptide (ICVVQDWGHHRCT (cyclic C2-C12)) (SEQ ID NO: 1) are described, in particular compstatin analogues that additionally possess useful physicochemical properties, such as increased solubility. These analogues include variants...