ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,725, issued on Oct. 14, was assigned to ZHEJIANG METON PHARMACEUTICAL Co. LTD (Zhejiang, China).
"ISO-citrate dehydrogenase (IDH) inhibitor" was invented by Jibin Yang (Shanghai), Feng Yan (Shanghai), Jinlong Zhu (Shanghai) and Jianxin Yang (Princeton, N.J.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compounds inhibiting the conversion of Alpha-KG to D-2-HG, pharmaceutically acceptable salts, hydrates, solvates or stereoisomers thereof and pharmaceutical compositions comprising the compounds. The compound and the pharmaceutical composition can effectively treat IDH associated diseases, including cancer."
The patent was filed on Sep...