US Patent Issued to ZATA PHARMACEUTICALS on May 13 for "Detection method for natural and modified small nucleic acids" (Massachusetts Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,225, issued on May 13, was assigned to ZATA PHARMACEUTICALS INC. (Worcester, Mass.).

"Detection method for natural and modified small nucleic acids" was invented by David R. Tabatadze (Worcester, Mass.) and Ivan B. Yanachkov (Shrewsbury, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a method for the detection of natural or modified nucleic acids by their sequence specific hybridization with charge-modified oligonucleotide probes having charge-modifying groups attached to their backbones. The charge-modifying groups partially or fully neutralize the net negative charge of the backbone of the oligonucleotide probes or r...