ALEXANDRIA, Va., Sept. 1 -- United States Patent no. 12,721,864, issued on Sept. 1, was assigned to Yes2NO GMBH (Dusseldorf, Germany).
"Skin treatment using NO" was invented by Tienush Rassaf (Essen, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions, methods and systems relating to the delivery of NO to intradermal targets are disclosed. Such delivery allows perturbation of molecular signaling such as may impact skin health, acne, aging, or hair follicle health. The compositions methods and systems overcome obstacles that inhibit effective delivery of NO in concentrations sufficient to influence intradermal signaling."
The patent was filed on June 27, 2025, under Application No. 19/252,324...