ALEXANDRIA, Va., March 17 -- United States Patent no. 12,578,320, issued on March 17, was assigned to Yale University (New Haven, Conn.).
"Methods and systems for physical expansion and imaging of biological samples" was invented by Ons M'Saad (New Haven, Conn.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and systems for physical expansion and imaging of biological samples are described herein. In one aspect of the disclosure, a method for preparing a biological sample for the purpose of generating images of its ultrastructure with an imaging instrument includes a) physically expanding the sample by at least a factor of two in at least one dimension; and b) bulk labeling a plurality of components o...