ALEXANDRIA, Va., July 14 -- United States Patent no. 12,678,493, issued on July 14, was assigned to Yale University (New Haven, Conn.).

"Compositions and methods for multiplexed tumor vaccination with endogenous gene activation" was invented by Sidi Chen (Milford, Conn.), Ryan D. Chow (San Jose, Calif.) and Guangchuan Wang (New Haven, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes compositions and methods for treating or preventing cancer. Embodiments include cell-based and viral vector-based vaccines that utilize gene expression activation systems to augment the product of endogenous genes to treat or prevent cancer."

The patent was filed on April 17, 2019, under Applic...