ALEXANDRIA, Va., June 9 -- United States Patent no. 12,648,989, issued on June 9, was assigned to XUZHOU HAIRUN BIOTECHNOLOGY Co. LTD. (Xuzhou, China).

"Recombinant BCG, preparation method therefor and application thereof" was invented by Yang Zhang (Zhumadian, China) and Pengjv Li (Xuzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Recombinant BCG, a preparation method therefor and an application thereof. A shuttle plasmid that can express a FimH protein on the surface of BCG is constructed, and a gene fragment that expresses the FimH protein is transformed into wild-type BCG to thereby obtain recombinant BCG. Upon verification, the recombinant BCG can express the FimH protein on the surface of BC...