US Patent Issued to XLIFESC on June 23 for "High-affinity TCR for recognizing SSX2 antigen" (Chinese Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,522, issued on June 23, was assigned to XLIFESC LTD. (Zhuhai, China).

"High-affinity TCR for recognizing SSX2 antigen" was invented by Shaopei Chen (Guangdong, China) and Hanli Sun (Guangdong, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a T-cell receptor (TCR) having the characteristic of binding to a KASEKIFYV(SEQ ID NO: 119)-HLA A0201 complex, wherein the binding affinity of the TCR to the KASEKIFYV(SEQ ID NO: 119)-HLA A0201 complex is at least two times that of a wild-type TCR to the KASEKIFYV(SEQ ID NO: 119)-HLA A0201 complex. The TCR may be used alone or in combination with a therapeutic agent, so as to target tumor cells p...