ALEXANDRIA, Va., June 16 -- United States Patent no. 12,303,384, issued on May 20, was assigned to Xeltis AG (Zurich).
"Electrospun heart valves" was invented by Jurgen Sander Miedema (Mels, Switzerland) and Martijn Antonius Johannes Cox (Budel, Netherlands).
According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and the resulting structures, like valve devices (e.g. heart or vessel) are provided made by electrospinning single shapes on mandrels with complex surface shapes. These single shapes are then shaped into valves with a plurality of leaflets. Three levels of complexity of shapes are described: 1) conical shapes, 2) a combination of conical and cylindrical shapes, and 3) a conical and/or cylindrical sha...