ALEXANDRIA, Va., July 14 -- United States Patent no. 12,678,599, issued on July 14, was assigned to World Vascular Inc. (Eden Prairie, Minn.).

"Medical guidewires for tortuous vessels" was invented by James Pokorney (Northfield, Minn.) and Matthew F. Ogle (Edina, Minn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Three groups of guidewire embodiments are described with particularly suitable structures for navigating circuitous vessels, especially blood vessels of the brain. Some of the guidewires have a hyperbolic taper that provides desired flexibility. In some embodiments, an integrated guide structure provides for extension in the blood vessel of a corewire to provide for extended reach of the guidewire...