ALEXANDRIA, Va., Sept. 1 -- United States Patent no. 12,723,076, issued on Sept. 1, was assigned to Wisconsin Alumni Research Foundation (Madison, Wis.).

"Human blood-brain barrier targeting antibodies" was invented by Eric V. Shusta (Madison, Wis.), Charles C. Stutz (Waltham, Mass.), Loukas Goulatis (Worcester, Mass.) and Julia Georgieva (Berlin).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides antibodies or antigen-binding fragments thereof including single chain variable fragment (scFv) antibodies that specifically bind to and translocate the blood-brain barrier and methods of use."

The patent was filed on Nov. 10, 2025, under Application No. 19/384,776.

*For further informat...