US Patent Issued to Wisconsin Alumni Research Foundation on June 23 for "Peptidic modulators of quorum sensing in Staphylococcus epidermidis" (Wisconsin Inventors)

ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,513, issued on June 23, was assigned to Wisconsin Alumni Research Foundation (Madison, Wis.).

"Peptidic modulators of quorum sensing in Staphylococcus epidermidis" was invented by Helen E. Blackwell (Middleton, Wis.) and Tian Yang (Madison, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Synthetic cyclic peptide modulators of the AgrC quorum sensing system of S. epidermidis. Synthetic agonists and antagonist of AgrC-I are described. Compounds capable of either pan-group or group-selective AgrC receptor inhibition in S. epidermidis were identified. Additionally, compounds that are species selective, and could be applied to selectively modulate ei...