ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,702,697, issued on Aug. 11, was assigned to Washington University (St. Louis).

"Compositions and methods for treatment of headache disorders and neuropathic pain" was invented by Yu-Qing Cao (St. Louis), Zhiyu Zhang (St. Louis), Rong Hu (St. Louis), Jintao Zhang (St. Louis) and Megan E. Cloud (St. Louis).

According to the abstract* released by the U.S. Patent & Trademark Office: "Among the various aspects of the present disclosure is the provision of compositions and methods of treating or preventing various headache disorders or neuropathic pain by increasing the number of Treg cells in a subject. In particular, low dose IL-2, rapamycin, statin or Treg cell administration are shown ...